Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and &#945;-fluoro-ß-alanine (FBAL).

Knikman, J E; de Vries, Niels; Rosing, H; Cats, A; Guchelaar, H-J; Beijnen, J H

Development of a UPLC-MS/MS Assay for the Quantitative Determination of Capecitabine, 5'-deoxy-5-fluorocytidine (5'-dFCR), 5'-deoxy-5-fluorouridine (5'-dFUR), 5'-fluorouracil (5-FU), and α-fluoro-ß-alanine (FBAL).

Knikman, J E; de Vries, Niels; Rosing, H; Cats, A; Guchelaar, H-J; Beijnen, J H.

Affiliation

Knikman JE; Division of Pharmacology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands.

Pharmazie ; 78(8): 107-112, 2023 08 01.

Article in En | MEDLINE | ID: mdl-37592424

Subject(s)

Fluorouracil; Prodrugs; Humans; Capecitabine; Tandem Mass Spectrometry; Chromatography, High Pressure Liquid; Chromatography, Liquid; Lithium; beta-Alanine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Fluorouracil Limits: Humans Language: En Journal: Pharmazie Journal subject: FARMACIA Year: 2023 Document type: Article Affiliation country: Netherlands Country of publication: Germany

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