Combinatorial Screening of Cationic Lipidoids Reveals How Molecular Conformation Affects Membrane-Targeting Antimicrobial Activity.

Jennings, James; Asceric, Dunja; Semeraro, Enrico Federico; Lohner, Karl; Malanovic, Nermina; Pabst, Georg

Jennings, James; Asceric, Dunja; Semeraro, Enrico Federico; Lohner, Karl; Malanovic, Nermina; Pabst, Georg.

Affiliation

Jennings J; Institute of Molecular Biosciences, University of Graz, NAWI Graz, 8010 Graz, Austria.
Asceric D; Field of Excellence BioHealth, University of Graz, 8010 Graz, Austria.
Semeraro EF; Institute of Molecular Biosciences, University of Graz, NAWI Graz, 8010 Graz, Austria.
Lohner K; Field of Excellence BioHealth, University of Graz, 8010 Graz, Austria.
Malanovic N; Institute of Molecular Biosciences, University of Graz, NAWI Graz, 8010 Graz, Austria.
Pabst G; Field of Excellence BioHealth, University of Graz, 8010 Graz, Austria.

ACS Appl Mater Interfaces ; 15(34): 40178-40190, 2023 Aug 30.

Article in En | MEDLINE | ID: mdl-37602460

Subject(s)

Anti-Bacterial Agents; Scattering, Small Angle; X-Ray Diffraction; Membranes; Cell Membrane; Anti-Bacterial Agents/pharmacology; Cations

Key words

combinatorial synthesis; lipidoids; membrane-active compounds; quaternary ammonium compounds; small-angle X-ray scattering

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anti-Bacterial Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Journal: ACS Appl Mater Interfaces Journal subject: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Year: 2023 Document type: Article Affiliation country: Austria Country of publication: United States

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