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A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Kim, Ho Young; Chia, Wai Kit; Hsieh, Chia-Ju; Saturnino Guarino, Dinahlee; Graham, Thomas J A; Lengyel-Zhand, Zsofia; Schneider, Mark; Tomita, Cosette; Lougee, Marshall G; Kim, Hee Jong; Pagar, Vinayak V; Lee, Hsiaoju; Hou, Catherine; Garcia, Benjamin A; Petersson, E James; O'Shea, Jennifer; Kotzbauer, Paul T; Mathis, Chester A; Lee, Virginia M-Y; Luk, Kelvin C; Mach, Robert H.
Affiliation
  • Kim HY; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Chia WK; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Hsieh CJ; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Saturnino Guarino D; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Graham TJA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Lengyel-Zhand Z; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Schneider M; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Tomita C; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Lougee MG; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
  • Kim HJ; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6303, United States.
  • Pagar VV; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
  • Lee H; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Hou C; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
  • Garcia BA; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6303, United States.
  • Petersson EJ; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
  • O'Shea J; Department of Neurology, Washington University School of Medicine, Saint Louis, Missouri 63110-1010, United States.
  • Kotzbauer PT; Department of Neurology, Washington University School of Medicine, Saint Louis, Missouri 63110-1010, United States.
  • Mathis CA; Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States.
  • Lee VM; Center for Neurodegenerative Disease Research, Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-2676, United States.
  • Luk KC; Center for Neurodegenerative Disease Research, Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-2676, United States.
  • Mach RH; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 1012, 231 S. 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
J Med Chem ; 66(17): 12185-12202, 2023 09 14.
Article in En | MEDLINE | ID: mdl-37651366
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Multiple System Atrophy / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Multiple System Atrophy / Alzheimer Disease Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2023 Document type: Article Affiliation country: United States