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Updates in the diagnosis and management of coeliac disease.
Shiha, Mohamed G; Chetcuti Zammit, Stefania; Elli, Luca; Sanders, David S; Sidhu, Reena.
Affiliation
  • Shiha MG; Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, United Kingdom; Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom. Electronic address: mohamed.shiha1@nhs.net.
  • Chetcuti Zammit S; Division of Gastroenterology, Mater Dei Hospital, Msida, Malta.
  • Elli L; Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
  • Sanders DS; Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, United Kingdom; Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
  • Sidhu R; Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield, United Kingdom; Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.
Article in En | MEDLINE | ID: mdl-37652646
ABSTRACT
Coeliac disease is a common autoimmune disorder induced by ingesting gluten, the protein component of wheat, barley, and rye. It is estimated that one-in-hundred people worldwide have coeliac disease, of whom the majority remain undiagnosed. Coeliac disease is characterized by a wide range of gastrointestinal and extraintestinal symptoms but can also present asymptomatically. Diagnosing coeliac disease depends on the concordance of clinical, serological and histopathological data. However, the diagnosis can be challenging and frequently overlooked. Undiagnosed coeliac disease is associated with an increased risk of complications and detrimental effects on quality of life. Early diagnosis and treatment of coeliac disease are necessary to reduce the risk of long-term complications.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Celiac Disease Type of study: Diagnostic_studies / Screening_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Best Pract Res Clin Gastroenterol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Celiac Disease Type of study: Diagnostic_studies / Screening_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Best Pract Res Clin Gastroenterol Journal subject: GASTROENTEROLOGIA Year: 2023 Document type: Article