Malaria in Pregnancy: Key Points for the Neonatologist.
Neoreviews
; 24(9): e539-e552, 2023 09 01.
Article
in En
| MEDLINE
| ID: mdl-37653081
ABSTRACT
In malaria-endemic regions, infection with the malaria parasite Plasmodium during pregnancy has been identified as a key modifiable factor in preterm birth, the delivery of low-birthweight infants, and stillbirth. Compared with their nonpregnant peers, pregnant persons are at higher risk for malaria infection. Malaria infection can occur at any time during pregnancy, with negative effects for the pregnant person and the fetus, depending on the trimester in which the infection is contracted. Pregnant patients who are younger, in their first or second pregnancy, and those coinfected with human immunodeficiency virus are at increased risk for malaria. Common infection prevention measures during pregnancy include the use of insecticide-treated bed nets and the use of intermittent preventive treatment with monthly doses of antimalarials, beginning in the second trimester in pregnant patients in endemic areas. In all trimesters, artemisinin-combination therapies are the first-line treatment for uncomplicated falciparum malaria, similar to treatment in nonpregnant adults. The World Health Organization recently revised its recommendations, now listing the specific medication artemether-lumefantrine as first-line treatment for uncomplicated malaria in the first trimester. While strong prevention and detection methods exist, use of these techniques remains below global targets. Ongoing work on approaches to treatment and prevention of malaria during pregnancy remains at the forefront of global maternal child health research.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Premature Birth
/
Malaria
/
Antimalarials
Type of study:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Limits:
Adult
/
Child
/
Female
/
Humans
/
Infant
/
Newborn
/
Pregnancy
Language:
En
Journal:
Neoreviews
Year:
2023
Document type:
Article
Affiliation country:
New Caledonia