Your browser doesn't support javascript.
loading
clifford B.4.1 , an allele of CG1603 , causes tissue overgrowth in the Drosophila melanogaster eye.
Nowaskie, Reagan R; Kitch, Ashley; Adams, Abby; Anandaraj, Abinaya; Apawan, Ethan; Bañuelos, Liliana; Betz, Cassandra J; Bogunia, Julia M; Buechlein, Nicholas; Burns, Morgan R; Collier, Hayley A; Collins, Zach; Combs, Kynzie; Dakarian, Vana D; Daniel, Abigail; De Jesus Iii, Conrad M; Erickson, John D; Estrada, Bianca; Estrada, Kevin; Fields, Sydney; Gabriel, Maya; Garcia, Rosario M; Gitamo, Sylvia; Granath, Emma; Hardin, Sabrina N; Hattling, Emily; Henriquez, Alexandra Vl; Hernandez, Destiny; Johnson, Luke; Kim, Annie H; Kolley, Lillian K; Larue, Katelynn M; Lockwood, Erin; Longoria, Nelia; Lopez, Cassandra; Lopez-Roca Fernandez, Rosario C; Lozano, Sofia; Manthie, Carissa; May, Trinity; Mehrzad, Zorah; Mendoza, Itzel; Mohan, Somya; Mounthachak, Claylan; Muyizere, Merveille; Myers, Margaret R; Newton, Jayce; Nwawueze, Amarachi; Paredes, Ariana J; Pezdek, Marissa N; Phat Nguyen, Hoang.
Affiliation
  • Nowaskie RR; University of Evansville, Evansville, Indiana, United States.
  • Kitch A; University of Evansville, Evansville, Indiana, United States.
  • Adams A; Northern Illinois University, DeKalb, Illinois, United States.
  • Anandaraj A; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Apawan E; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Bañuelos L; Northern Illinois University, DeKalb, Illinois, United States.
  • Betz CJ; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Bogunia JM; Northern Illinois University, DeKalb, Illinois, United States.
  • Buechlein N; University of Evansville, Evansville, Indiana, United States.
  • Burns MR; Northern Illinois University, DeKalb, Illinois, United States.
  • Collier HA; Northern Illinois University, DeKalb, Illinois, United States.
  • Collins Z; Northern Illinois University, DeKalb, Illinois, United States.
  • Combs K; University of Evansville, Evansville, Indiana, United States.
  • Dakarian VD; Northern Illinois University, DeKalb, Illinois, United States.
  • Daniel A; University of Evansville, Evansville, Indiana, United States.
  • De Jesus Iii CM; University of Evansville, Evansville, Indiana, United States.
  • Erickson JD; University of Evansville, Evansville, Indiana, United States.
  • Estrada B; Northern Illinois University, DeKalb, Illinois, United States.
  • Estrada K; Northern Illinois University, DeKalb, Illinois, United States.
  • Fields S; Northern Illinois University, DeKalb, Illinois, United States.
  • Gabriel M; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Garcia RM; Northern Illinois University, DeKalb, Illinois, United States.
  • Gitamo S; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Granath E; Northern Illinois University, DeKalb, Illinois, United States.
  • Hardin SN; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Hattling E; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Henriquez AV; Northern Illinois University, DeKalb, Illinois, United States.
  • Hernandez D; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Johnson L; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Kim AH; University of Evansville, Evansville, Indiana, United States.
  • Kolley LK; University of Evansville, Evansville, Indiana, United States.
  • Larue KM; Northern Illinois University, DeKalb, Illinois, United States.
  • Lockwood E; Northern Illinois University, DeKalb, Illinois, United States.
  • Longoria N; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Lopez C; Northern Illinois University, DeKalb, Illinois, United States.
  • Lopez-Roca Fernandez RC; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Lozano S; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Manthie C; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • May T; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Mehrzad Z; University of Evansville, Evansville, Indiana, United States.
  • Mendoza I; Northern Illinois University, DeKalb, Illinois, United States.
  • Mohan S; The University of Texas at San Antonio, San Antonio, Texas, United States.
  • Mounthachak C; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
  • Muyizere M; Northern Illinois University, DeKalb, Illinois, United States.
  • Myers MR; Northern Illinois University, DeKalb, Illinois, United States.
  • Newton J; Northern Illinois University, DeKalb, Illinois, United States.
  • Nwawueze A; Northern Illinois University, DeKalb, Illinois, United States.
  • Paredes AJ; University of Evansville, Evansville, Indiana, United States.
  • Pezdek MN; Northern Illinois University, DeKalb, Illinois, United States.
  • Phat Nguyen H; Anoka-Ramsey Community College, Coon Rapids, Minnesota, United States.
MicroPubl Biol ; 20232023.
Article in En | MEDLINE | ID: mdl-37680216
ABSTRACT
Mutant B.4.1 , generated via EMS mutagenesis in Drosophila melanogaster , was studied by undergraduate students participating in the Fly-CURE. After inducing genetically mosaic tissue in the adult eye, B.4.1 mutant tissue displays a robust increase in cell division and a rough appearance. Complementation mapping and sequence analysis identified a nonsense mutation in the gene CG1603 , which we named clifford ( cliff ) due to observed increases in red-pigmented mutant tissue compared to controls. cliff encodes a zinc finger-containing protein implicated in transcriptional control. RNAi knockdown of cliff similarly results in rough eyes, confirming a role for Cliff in eye development.
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: MicroPubl Biol Year: 2023 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Etiology_studies Language: En Journal: MicroPubl Biol Year: 2023 Document type: Article Affiliation country: United States