Undiagnosed Factor VII Deficiency in Cardiac Surgery Complicated by Bleeding: A Case Report.
A A Pract
; 17(9): e01713, 2023 Sep 01.
Article
in En
| MEDLINE
| ID: mdl-37681735
ABSTRACT
Rare bleeding disorders in the perioperative period call for targeted resuscitation strategies. Factor VII deficiency, for instance, is often corrected with exogenous administration of recombinant factor VIIa. This activated clotting factor, initially designed for patients with hemophilia A or B with factor inhibitors, is gaining popularity as a salvage therapy for severe and persistent traumatic and surgical bleeding. This article describes the management of a cardiothoracic surgical patient with undiagnosed isolated factor VII deficiency who experienced significant postoperative bleeding which subsided after the administration of recombinant factor VIIa. In this case, EXTEM failed to detect a clotting factor deficiency.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Factor VII Deficiency
/
Cardiac Surgical Procedures
/
Hemophilia A
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Humans
Language:
En
Journal:
A A Pract
Year:
2023
Document type:
Article