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Novel small molecule-mediated restoration of the surface expression and anion exchange activity of mutated pendrin causing Pendred syndrome and DFNB4.
Jung, Jinsei; Noh, Shin Hye; Jo, Sungwoo; Song, Doona; Kang, Min Jin; Shin, Mi Hwa; Lee, Hyun Jae; Pyun, Jae-Chul; Namkung, Wan; Han, Gyoonhee; Lee, Min Goo; Choi, Jae Young.
Affiliation
  • Jung J; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Won-Sang Lee Institute for Hearing Loss, Seoul 03722, Republic of Korea.
  • Noh SH; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
  • Jo S; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
  • Song D; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea; Department of Integrated OMICS for Biomedical Science, Yonsei University, Seoul 03722, Republic of Korea; Translational Research Center for Protein Function Control, Department of Biotech
  • Kang MJ; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Won-Sang Lee Institute for Hearing Loss, Seoul 03722, Republic of Korea.
  • Shin MH; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Won-Sang Lee Institute for Hearing Loss, Seoul 03722, Republic of Korea.
  • Lee HJ; Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, USA.
  • Pyun JC; Department of Materials Science and Engineering, Yonsei University, Seoul 03722, Republic of Korea.
  • Namkung W; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea. Electronic address: wnamkung@yonsei.ac.kr.
  • Han G; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea; Department of Integrated OMICS for Biomedical Science, Yonsei University, Seoul 03722, Republic of Korea; Translational Research Center for Protein Function Control, Department of Biotech
  • Lee MG; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Republic of Korea, Seoul 03722, Republic of Korea. Electronic address: mlee@yuhs.ac.
  • Choi JY; Department of Otorhinolaryngology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul 03722, Republic of Korea; Won-Sang Lee Institute for Hearing Loss, Seoul 03722, Republic of Korea. Electronic address: jychoi@yuhs.ac.
Biomed Pharmacother ; 167: 115445, 2023 Nov.
Article in En | MEDLINE | ID: mdl-37690388
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Biomed Pharmacother Year: 2023 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Biomed Pharmacother Year: 2023 Document type: Article