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Mast cell deficiency improves cognition and enhances disease-associated microglia in 5XFAD mice.
Lin, Chih-Chung Jerry; Herisson, Fanny; Le, Hoang; Jaafar, Nader; Chetal, Kashish; Oram, Mary K; Flynn, Kelly L; Gavrilles, Evan P; Sadreyev, Ruslan I; Schiffino, Felipe L; Tanzi, Rudolph E.
Affiliation
  • Lin CJ; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Herisson F; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Le H; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Jaafar N; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Chetal K; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
  • Oram MK; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Flynn KL; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Gavrilles EP; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Sadreyev RI; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
  • Schiffino FL; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
  • Tanzi RE; Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA; Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Charlestown, MA 02129, USA. Electronic address: tanzi@helix.mgh.harvard
Cell Rep ; 42(9): 113141, 2023 09 26.
Article in En | MEDLINE | ID: mdl-37713312

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Alzheimer Disease Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Microglia / Alzheimer Disease Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Cell Rep Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States