Future Directions of Allergen Immunotherapy for Allergic Rhinitis: Experts' Perspective.
J Allergy Clin Immunol Pract
; 12(1): 32-44, 2024 01.
Article
in En
| MEDLINE
| ID: mdl-37716529
ABSTRACT
Allergen immunotherapy (AIT) is broadly used all over the world as the only available disease-modifying treatment option. The aim of this experts' perspective is to address 7 important unmet needs for the further direction of AIT and to provide the readership with the authors' positions on these topics. An international group of experts in the field of AIT have formulated 7 important aspects for the future position of AIT, performed a current literature review, and proposed a consented position on these topics. The aspects discussed and consented by the authors include (1) alternative routes of allergen application in AIT, (2) potential of recombinant vaccines, (3) the role of allergy diagnosis based on component-resolved diagnosis for AIT composition, (4) the impact of COVID-19 vaccination for further innovations in AIT, (5) potential of combining biologics to AIT, (6) future innovations in high-risk children/adolescents, and (7) the future regulatory position on AIT. Important unmet needs and topics for AIT have been addressed in this expert review. The authors' views and personal position on these 7 aspects have also been elaborated.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rhinitis, Allergic
/
COVID-19 Vaccines
Limits:
Adolescent
/
Child
/
Humans
Language:
En
Journal:
J Allergy Clin Immunol Pract
Year:
2024
Document type:
Article
Affiliation country:
Germany