Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems.

Dean, Brian; Scarr, Elizabeth

Dean, Brian; Scarr, Elizabeth.

Affiliation

Dean B; The Molecular Psychiatry Laboratory, The Florey Institute for Neuroscience and Mental Health, Parkville, Australia.
Scarr E; Florey Department of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, Australia.

World J Biol Psychiatry ; 25(1): 54-64, 2024.

Article in En | MEDLINE | ID: mdl-37722808

Subject(s)

Lithium; Valproic Acid; Rats; Animals; Valproic Acid/pharmacology; Valproic Acid/therapeutic use; Lithium/pharmacology; Lithium/therapeutic use; Lithium Compounds/pharmacology; Gene Expression; RNA; Neurotransmitter Agents; Antimanic Agents/pharmacology; Antimanic Agents/therapeutic use

Key words

Lithium; gene expression; rat cortex; sodium valproate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Valproic Acid / Lithium Limits: Animals Language: En Journal: World J Biol Psychiatry Journal subject: PSIQUIATRIA Year: 2024 Document type: Article Affiliation country: Australia Country of publication: United kingdom

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