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Microbiota-derived butyrate dampens linaclotide stimulation of the guanylate cyclase C pathway in patient-derived colonoids.
Velez Lopez, Alejandro; Waddell, Amanda; Antonacci, Simona; Castillo, Daniel; Santucci, Neha; Ollberding, Nicholas J; Eshleman, Emily M; Denson, Lee A; Alenghat, Theresa.
Affiliation
  • Velez Lopez A; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Waddell A; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Antonacci S; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Castillo D; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Santucci N; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Ollberding NJ; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Eshleman EM; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Denson LA; Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
  • Alenghat T; Division of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Ohio, Cincinnati, USA.
Neurogastroenterol Motil ; 35(12): e14681, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37736865

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Irritable Bowel Syndrome / Microbiota Type of study: Prognostic_studies Aspects: Patient_preference Limits: Child / Humans Language: En Journal: Neurogastroenterol Motil Journal subject: GASTROENTEROLOGIA / NEUROLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Irritable Bowel Syndrome / Microbiota Type of study: Prognostic_studies Aspects: Patient_preference Limits: Child / Humans Language: En Journal: Neurogastroenterol Motil Journal subject: GASTROENTEROLOGIA / NEUROLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: United kingdom