Your browser doesn't support javascript.
loading
Determinants of phase angle in Japanese patients with diabetes.
Muramae, Naokazu; Matsuda, Tomokazu; Inagaki, Satoshi; Takahashi, Hiroaki; Abe, Kozue; Nakatani, Saki; Takahashi, Michiko; Kato, Kenji; Sakaguchi, Kazuhiko; Ogawa, Wataru.
Affiliation
  • Muramae N; Department of General Internal Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017 Japan.
  • Matsuda T; Department of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, Kobe, Japan.
  • Inagaki S; Matsuda Diabetes Clinic, Kobe, Japan.
  • Takahashi H; School of Nursing, Kobe City College of Nursing, Kobe, Japan.
  • Abe K; Matsuda Diabetes Clinic, Kobe, Japan.
  • Nakatani S; Matsuda Diabetes Clinic, Kobe, Japan.
  • Takahashi M; Department of Nutrition, Kobe University Hospital, Kobe, Japan.
  • Kato K; Department of Nutrition, Kobe University Hospital, Kobe, Japan.
  • Sakaguchi K; Faculty of Nursing Science, Kobe Women's University, Kobe, Japan.
  • Ogawa W; Department of General Internal Medicine, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, 650-0017 Japan.
Diabetol Int ; 14(4): 339-343, 2023 Oct.
Article in En | MEDLINE | ID: mdl-37781466
Phase angle, obtained using bioelectrical impedance analysis, non-invasively reflects the whole-body cellular condition and nutritional status and may be helpful as a prognostic factor. Patients with diabetes had a smaller phase angle than healthy subjects. However, the clinical significance of phase angle has not yet been elucidated. Therefore, the purpose of this study was to clarify the relationship between phase angle and HbA1c in patients with diabetes and the clinical relevance of phase angle. A retrospective, multicenter, cross-sectional study was conducted with Japanese patients with diabetes. Body composition was determined with bioelectrical impedance analysis, and this was used to obtain phase angle. Phase angle was assessed in relation to clinical parameters, body composition parameters, and HbA1c levels. A total of 655 patients were enrolled (400 men and 255 women, aged 57.1 ± 14.8 years, body mass index 25.6 ± 5.2 kg/m2, HbA1c 8.1 ± 1.9%). Even in patients with diabetes, the phase angle was higher in men than in women and did not differ between the types of diabetes. Multiple regression analysis, performed with phase angle as the objective variable, and age, sex, diabetes type, HbA1c, albumin level, and body mass index as explanatory variables, revealed that phase angle was negatively affected by HbA1c (B = - 0.043, 95% Confidence interval: - 0.07 to - 0.02, p < 0.001). HbA1c, age, sex, albumin level, and body mass index were independent determinants of phase angle in participants with diabetes.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Observational_studies / Prognostic_studies Language: En Journal: Diabetol Int Year: 2023 Document type: Article Country of publication: Japan

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Clinical_trials / Observational_studies / Prognostic_studies Language: En Journal: Diabetol Int Year: 2023 Document type: Article Country of publication: Japan