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Discovery of novel TLR4/MD-2 inhibitors: Receptor structure-based virtual screening studies and anti-inflammatory evaluation.
Zhang, Tengyue; Xing, Siqi; Du, Jiyu; Xia, Jucheng; Dong, Shuanghong; Li, Zeng; Liu, Zhicheng; Song, Yang.
Affiliation
  • Zhang T; Department of Oncology, Anhui Provincial Cancer Hospital, West Branch of the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui In
  • Xing S; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China; The Affiliated Suqian First People's Hospital of Nanjing Medical University, SuQian 223800, China.
  • Du J; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China.
  • Xia J; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China.
  • Dong S; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China.
  • Li Z; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China. Electronic address: lizeng@ahmu.edu.cn.
  • Liu Z; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China. Electronic address: liuzhicheng@ahmu.edu.cn.
  • Song Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei 230000, China; Department of Pain, The First Affiliated Hospital of Anhui Medical University, Anhui Medical Uiversity, Hefei 230032, China.
Bioorg Chem ; 141: 106880, 2023 12.
Article in En | MEDLINE | ID: mdl-37783098
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Antigen 96 / Toll-Like Receptor 4 / Anti-Inflammatory Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Bioorg Chem Year: 2023 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Antigen 96 / Toll-Like Receptor 4 / Anti-Inflammatory Agents Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals Language: En Journal: Bioorg Chem Year: 2023 Document type: Article Country of publication: United States