Correlation between vitiligo antibodies and extent of depigmentation in vitiligo.
J Am Acad Dermatol
; 15(5 Pt 1): 978-81, 1986 Nov.
Article
in En
| MEDLINE
| ID: mdl-3782537
ABSTRACT
We correlated the level of vitiligo antibodies to the extent of depigmentation in thirty-two patients with vitiligo. Vitiligo antibodies were assayed by protein A-sepharose immunoprecipitation method. Antibodies were present in four of eight (50%) patients with minimal vitiligo (less than 2% body surface involved), in nine of ten (90%) patients with moderate vitiligo (2 to 5% surface involved), and in thirteen of fourteen (93%) patients with more extensive disease (greater than 5% surface involved). The level of vitiligo antibodies in the three groups expressed as a binding index was 2.9% +/- 2.03, 5.6% +/- 2.92, and 8.0% +/- 3.03 SD, respectively. These results suggest that there is a relation between the incidence and level of vitiligo antibodies and the extent of depigmentation in vitiligo.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Vitiligo
/
Skin Pigmentation
/
Antibodies
Limits:
Adult
/
Humans
Language:
En
Journal:
J Am Acad Dermatol
Year:
1986
Document type:
Article