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Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity.
Miao, Jinmin; Bai, Yunpeng; Miao, Yiming; Qu, Zihan; Dong, Jiajun; Zhang, Ruo-Yu; Aggarwal, Devesh; Jassim, Brenson A; Nguyen, Quyen; Zhang, Zhong-Yin.
Affiliation
  • Miao J; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Bai Y; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Miao Y; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Qu Z; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Dong J; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Zhang RY; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Aggarwal D; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Jassim BA; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Nguyen Q; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Zhang ZY; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Molecules ; 28(19)2023 Oct 06.
Article in En | MEDLINE | ID: mdl-37836790
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Neoplasms Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: Switzerland
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Neoplasms Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: United States Country of publication: Switzerland