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Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, ß-secretase, and amyloid ß aggregation as potential treatment of Alzheimer's disease.
Zareba, Paula; Latka, Kamil; Mazur, Gabriela; Gryzlo, Beata; Pasieka, Anna; Godyn, Justyna; Panek, Dawid; Skrzypczak-Wiercioch, Anna; Höfner, Georg C; Latacz, Gniewomir; Maj, Maciej; Espargaró, Alba; Sabaté, Raimon; Józwiak, Krzysztof; Wanner, Klaus T; Salat, Kinga; Malawska, Barbara; Kulig, Katarzyna; Bajda, Marek.
Affiliation
  • Zareba P; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Latka K; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Mazur G; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Gryzlo B; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Pasieka A; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Godyn J; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Panek D; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Skrzypczak-Wiercioch A; Department of Animal Anatomy and Preclinical Sciences, University Centre of Veterinary Medicine JU-UA, University of Agriculture in Kraków, Mickiewicz 24/28 St., 30-059, Kraków, Poland.
  • Höfner GC; Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München Butenandtstr., 5-13, 81377, Munich, Germany.
  • Latacz G; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Maj M; Department of Biopharmacy, Medical University of Lublin, W. Chodzki 4a St., 20-093, Lublin, Poland.
  • Espargaró A; Department of Pharmacy and Pharmaceutical Technology and Physical-Chemistry, School of Pharmacy and Food Sciences, University of Barcelona, Av Joan XXIII 27-31, 08028, Barcelona, Spain; Institute of Nanoscience and Nanotechnology (IN2UB), Av Joan XXIII, S/N, 08028, Barcelona, Spain.
  • Sabaté R; Department of Pharmacy and Pharmaceutical Technology and Physical-Chemistry, School of Pharmacy and Food Sciences, University of Barcelona, Av Joan XXIII 27-31, 08028, Barcelona, Spain; Institute of Nanoscience and Nanotechnology (IN2UB), Av Joan XXIII, S/N, 08028, Barcelona, Spain.
  • Józwiak K; Department of Biopharmacy, Medical University of Lublin, W. Chodzki 4a St., 20-093, Lublin, Poland.
  • Wanner KT; Department of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München Butenandtstr., 5-13, 81377, Munich, Germany.
  • Salat K; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Malawska B; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Kulig K; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland.
  • Bajda M; Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9 St., 30-688, Kraków, Poland. Electronic address: marek.bajda@uj.edu.pl.
Eur J Med Chem ; 261: 115832, 2023 Dec 05.
Article in En | MEDLINE | ID: mdl-37837674
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Butyrylcholinesterase / Alzheimer Disease Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: Poland Country of publication: France
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Butyrylcholinesterase / Alzheimer Disease Limits: Animals Language: En Journal: Eur J Med Chem Year: 2023 Document type: Article Affiliation country: Poland Country of publication: France