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Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease.
Kishimoto, Takashi Kei; Fournier, Max; Michaud, Alicia; Rizzo, Gina; Roy, Christopher; Capela, Teresa; Nukolova, Natasha; Li, Ning; Doyle, Liam; Fu, Fen-Ni; VanDyke, Derek; Traber, Peter G; Spangler, Jamie B; Leung, Sheldon S; Ilyinskii, Petr O.
Affiliation
  • Kishimoto TK; Selecta Biosciences, Watertown, MA, 02472, USA. Electronic address: kkishimoto@selectabio.com.
  • Fournier M; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Michaud A; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Rizzo G; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Roy C; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Capela T; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Nukolova N; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Li N; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Doyle L; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Fu FN; Selecta Biosciences, Watertown, MA, 02472, USA.
  • VanDyke D; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Traber PG; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Spangler JB; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine
  • Leung SS; Selecta Biosciences, Watertown, MA, 02472, USA.
  • Ilyinskii PO; Selecta Biosciences, Watertown, MA, 02472, USA.
J Autoimmun ; 140: 103125, 2023 Oct 14.
Article in En | MEDLINE | ID: mdl-37844543
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Document type: Article Country of publication: United kingdom