Cleveland Clinic Continuous-Flow Total Artificial Heart: Progress Report and Technology Update.
ASAIO J
; 70(2): 116-123, 2024 Feb 01.
Article
in En
| MEDLINE
| ID: mdl-37851000
ABSTRACT
Cleveland Clinic's continuous-flow total artificial heart (CFTAH) is being developed at our institution and has demonstrated system reliability and optimal performance. Based on the results from recent chronic in vivo experiments, CFTAH has been revised, especially to improve biocompatibility. The purpose of this article is to report our progress in developing CFTAH. To improve biocompatibility, the right impeller, the pump housing, and the motor were reviewed for design revision. Updated design features were based on computational fluid dynamics analysis and observations from in vitro and in vivo studies. A new version of CFTAH was created, manufactured, and tested. All hemodynamic and pump-related parameters were observed and found to be within the intended ranges, and the new CFTAH yielded acceptable biocompatibility. Cleveland Clinic's continuous-flow total artificial heart has demonstrated reliable performance, and has shown satisfactory progress in its development.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Heart-Assist Devices
/
Heart, Artificial
Language:
En
Journal:
ASAIO J
Journal subject:
TRANSPLANTE
Year:
2024
Document type:
Article