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Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.
Soeda, Kotaro; Sasako, Takayoshi; Enooku, Kenichiro; Kubota, Naoto; Kobayashi, Naoki; Ikushima, Yoshiko Matsumoto; Awazawa, Motoharu; Bouchi, Ryotaro; Toda, Gotaro; Yamada, Tomoharu; Nakatsuka, Takuma; Tateishi, Ryosuke; Kakiuchi, Miwako; Yamamoto, Shogo; Tatsuno, Kenji; Atarashi, Koji; Suda, Wataru; Honda, Kenya; Aburatani, Hiroyuki; Yamauchi, Toshimasa; Fujishiro, Mitsuhiro; Noda, Tetsuo; Koike, Kazuhiko; Kadowaki, Takashi; Ueki, Kohjiro.
Affiliation
  • Soeda K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Sasako T; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Enooku K; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Kubota N; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Kobayashi N; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Ikushima YM; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Awazawa M; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Bouchi R; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Toda G; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Yamada T; Diabetes and Metabolism Information Center, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Nakatsuka T; Department of Molecular Diabetic Medicine, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
  • Tateishi R; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Kakiuchi M; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Yamamoto S; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Tatsuno K; Department of Gastroenterology, The University of Tokyo, Tokyo, Japan.
  • Atarashi K; Genome Science Division, The University of Tokyo, Tokyo, Japan.
  • Suda W; Genome Science Division, The University of Tokyo, Tokyo, Japan.
  • Honda K; Genome Science Division, The University of Tokyo, Tokyo, Japan.
  • Aburatani H; Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
  • Yamauchi T; RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, Japan.
  • Fujishiro M; RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, Japan.
  • Noda T; Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
  • Koike K; RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, Japan.
  • Kadowaki T; Genome Science Division, The University of Tokyo, Tokyo, Japan.
  • Ueki K; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Nat Commun ; 14(1): 6584, 2023 10 18.
Article in En | MEDLINE | ID: mdl-37852976
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Diabetes Mellitus, Experimental / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Limits: Animals / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Diabetes Mellitus, Experimental / Non-alcoholic Fatty Liver Disease / Liver Neoplasms Limits: Animals / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Document type: Article Affiliation country: Japan