Back To Basics: Theory of Thrombus Formation and Potential Implications for Therapies?
Tech Vasc Interv Radiol
; 26(2): 100894, 2023 Jun.
Article
in En
| MEDLINE
| ID: mdl-37865449
ABSTRACT
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and potentially fatal condition. Despite existing treatments, recurrence rates and complications remain high. Understanding the pathophysiology of thrombus formation is crucial for developing effective therapies. This narrative review provides an overview of the critical elements of acute and chronic DVT, presents a theoretical framework for understanding thrombus formation, and discusses potential implications for therapeutic interventions. In addition, a hypothesis of thrombus formation is formulated, encompassing all elements described in this work.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pulmonary Embolism
/
Thrombosis
/
Venous Thrombosis
/
Venous Thromboembolism
Limits:
Humans
Language:
En
Journal:
Tech Vasc Interv Radiol
Journal subject:
ANGIOLOGIA
/
RADIOLOGIA
Year:
2023
Document type:
Article
Affiliation country:
Panama