The risk assessment of uveitis after COVID-19 diagnosis: A multicenter population-based study.
J Med Virol
; 95(10): e29188, 2023 10.
Article
in En
| MEDLINE
| ID: mdl-37881132
ABSTRACT
Reports on uveitis after COVID-19 have been limited. Our objective was to examine the risk of uveitis among COVID-19 patients. This was a retrospective cohort study based on the TriNetX platform. The exposure group was patients with positive laboratory test result for SARS-CoV-2 and the comparison group was those tested negative for COVID-19 throughout the study period. The endpoint is the new diagnoses of uveitis. This study composed of 2 105 424 patients diagnosed with COVID-19 (55.4% female; 62.5% white; mean age at index 40.7 years) and 2 105 424 patients (55.4% female; 62.4% white; mean age at index 40.7 years) who never had COVID-19. There was significantly increased risk of new diagnosis of uveitis since the first month after diagnosis of COVID-19 compared with matched controls (HR 1.18, 95% CI 1.03-1.34) up to 24 months (HR 1.16, 95% CI 1.09-1.22). Our findings strengthen those previously raised by case series with a larger and multicenter study. We found that uveitis was significantly associated with COVID-19 infection. Our findings reiterate the need for careful investigation as well as increased awareness from ophthalmologists in considering the possibility of COVID-19 in vulnerable patients with new presentation of uveitis.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uveitis
/
COVID-19
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
J Med Virol
Year:
2023
Document type:
Article
Affiliation country:
Taiwan