[Effect of neutral solvents on lectin binding of healthy and psoriatic epidermis]. / Einfluss neutraler Lösungsmittel auf die Lektinbindung gesunder und psoriatischer Epidermis.

ABSTRACT

We studied the influence of neutral solvents on epidermal lectin binding in normal and lesional psoriatic skin. 1% solution of Tween 80 or Triton X-100 had no effect on the binding of the following lectins PHA, ConA, and LCA. The HPA staining of the str. spinosum in normal skin, however, was completely removed by neutral solvents. In psoriatic skin, str. spinosum staining with HPA was resistant. Our results are discussed in the light of an altered keratinocyte maturation in psoriasis.