Four new alkaloids from the roots of Dactylicapnos scandens.
J Asian Nat Prod Res
; 26(2): 248-258, 2024 Feb.
Article
in En
| MEDLINE
| ID: mdl-37905564
ABSTRACT
Four new alkaloids (1 - 4), together with five known ones (5 - 9), were isolated from the bulbs of Dactylicapnos scandens. The structures were determined by analysis of their spectroscopic data and quantum-chemical calculations. All the isolates were tested for their ability to modulate neuronal Ca2+ mobilization in primary cultured neocortical neurons. Compound 8 inhibited spontaneous Ca2+ oscillations at low micromolar concentrations.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Alkaloids
Language:
En
Journal:
J Asian Nat Prod Res
Journal subject:
BOTANICA
/
QUIMICA
Year:
2024
Document type:
Article
Affiliation country:
China