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CRISPR/Cas9-mediated knock-in of BRCA1/2 mutations restores response to olaparib in pancreatic cancer cell lines.
Witz, Andréa; Dardare, Julie; Francois, Aurélie; Husson, Marie; Rouyer, Marie; Demange, Jessica; Merlin, Jean-Louis; Gilson, Pauline; Harlé, Alexandre.
Affiliation
  • Witz A; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France. a.witz@nancy.unicancer.fr.
  • Dardare J; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France. a.witz@nancy.unicancer.fr.
  • Francois A; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
  • Husson M; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
  • Rouyer M; Université de Lorraine, CNRS UMR 7039 CRAN, Vandœuvre-lès-Nancy, France.
  • Demange J; Département Recherche, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
  • Merlin JL; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
  • Gilson P; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
  • Harlé A; Département de Biopathologie, Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, France.
Sci Rep ; 13(1): 18741, 2023 10 31.
Article in En | MEDLINE | ID: mdl-37907567
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma Limits: Humans Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: France Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma Limits: Humans Language: En Journal: Sci Rep Year: 2023 Document type: Article Affiliation country: France Country of publication: United kingdom