Core-genome multilocus sequence typing and core-SNP analysis of Clostridium neonatale strains isolated in different spatio-temporal settings.
Microbiol Spectr
; 11(6): e0276623, 2023 Dec 12.
Article
in En
| MEDLINE
| ID: mdl-37909758
ABSTRACT
IMPORTANCE Clostridium neonatale has been isolated from the fecal samples of asymptomatic neonates and cases of necrotizing enterocolitis (NEC). Taking advantage of a large collection of independent strains isolated from different spatio-temporal settings, we developed and established a cgMLST scheme for the molecular typing of C. neonatale. Both the cgMLST and cgSNP methods demonstrate comparable discrimination power. Results indicate geographic- and temporal- independent clustering of C. neonatale NEC-associated strains. No specific cgMLST clade of C. neonatale was genetically associated with NEC.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Clostridium
/
Enterocolitis, Necrotizing
Limits:
Humans
/
Newborn
Language:
En
Journal:
Microbiol Spectr
Year:
2023
Document type:
Article
Affiliation country:
France