Role of ALS-associated OPTN-K489E mutation in neuronal cell-death regulation.

Mishra, Dibyakanti; Narain, Priyam; Dave, Upma; Gomes, James

Mishra, Dibyakanti; Narain, Priyam; Dave, Upma; Gomes, James.

Affiliation

Mishra D; Neurodegenerative Biology & System Biology Lab, Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Narain P; Centre for Genomics & Systems Biology, New York University, Abu Dhabi, United Arab Emirates.
Dave U; Neurodegenerative Biology & System Biology Lab, Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Gomes J; Neurodegenerative Biology & System Biology Lab, Kusuma School of Biological Sciences, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India. Electronic address: jgomes@bioschool.iitd.ac.in.

Mol Cell Neurosci ; 127: 103904, 2023 Dec.

Article in En | MEDLINE | ID: mdl-37918554

Subject(s)

Amyotrophic Lateral Sclerosis; Neuroblastoma; Humans; Amyotrophic Lateral Sclerosis/metabolism; Mutation; Cell Death; Apoptosis/genetics

Key words

ALS; Apoptosis; Autophagy; K489E mutation; Necroptosis; OPTN

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amyotrophic Lateral Sclerosis / Neuroblastoma Limits: Humans Language: En Journal: Mol Cell Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2023 Document type: Article Affiliation country: India Country of publication: United States

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