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Phytoprostanes and phytofurans: Bioactive compounds in aerial parts of Acacia cyanophylla Lindl.
Mersni, Marwa; Zhou, Bingqing; Reversat, Guillaume; Khouja, Mohamed Larbi; Guy, Alexandre; Oger, Camille; Galano, Jean-Marie; Durand, Thierry; Messaoud, Chokri; Vigor, Claire.
Affiliation
  • Mersni M; University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of Nanobiotechnology and Valorization of Medicinal Phytoresources, Centre Urbain Nord, BP 676, 1080 Tunis Cedex, Tunisia; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pô
  • Zhou B; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Reversat G; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Khouja ML; University of Carthage, National Institute of Research in Rural Engineering, Waters and Forests, BP 10, Ariana 2080, Tunisia.
  • Guy A; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Oger C; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Galano JM; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Durand T; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France.
  • Messaoud C; University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of Nanobiotechnology and Valorization of Medicinal Phytoresources, Centre Urbain Nord, BP 676, 1080 Tunis Cedex, Tunisia.
  • Vigor C; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, Pôle Chimie Balard Recherche, University of Montpellier, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France. Electronic address: claire.vigor@umontpellier.fr.
Fitoterapia ; 172: 105717, 2024 Jan.
Article in En | MEDLINE | ID: mdl-37931720
The relevance of oxylipins as biomarkers of oxidative stress has been established in recent years. Phytoprostanes and phytofurans are plant metabolites derived from peroxidation of α-linolenic acid (ALA) induced by ROS. Previous findings have suggested new valuable biological properties for these new active compounds in the frame of diverse pathophysiological situations and health constraints. Lipidomic profiling of different aerial parts of the same Acacia cyanophylla Lindl. specimen, was evaluated for the first time here, using LC-MS/MS technology. Analysis revealed the existence of six PhytoPs and three PhytoFs. Stems have the highest amount of these metabolites with 179.35 ng/g and 320.79 ng/g respectively. This first complete profile paves the way to explore Acacia cyanophylla Lindl. as a source of plant oxylipins for therapeutic or pharmaceutical uses.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acacia / Oxylipins Language: En Journal: Fitoterapia Year: 2024 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acacia / Oxylipins Language: En Journal: Fitoterapia Year: 2024 Document type: Article Country of publication: Netherlands