Metabolomics of natural samples: A tutorial review on the latest technologies.
J Sep Sci
; 47(1): e2300588, 2024 Jan.
Article
in En
| MEDLINE
| ID: mdl-37942863
ABSTRACT
Metabolomics is the study of metabolites present in a living system. It is a rapidly growing field aimed at discovering novel compounds, studying biological processes, diagnosing diseases, and ensuring the quality of food products. Recently, the analysis of natural samples has become important to explore novel bioactive compounds and to study how environment and genetics affect living systems. Various metabolomics techniques, databases, and data analysis tools are available for natural sample metabolomics. However, choosing the right method can be a daunting exercise because natural samples are heterogeneous and require untargeted approaches. This tutorial review aims to compile the latest technologies to guide an early-career scientist on natural sample metabolomics. First, different extraction methods and their pros and cons are reviewed. Second, currently available metabolomics databases and data analysis tools are summarized. Next, recent research on metabolomics of milk, honey, and microbial samples is reviewed. Finally, after reviewing the latest trends in technologies, a checklist is presented to guide an early-career researcher on how to design a metabolomics project. In conclusion, this review is a comprehensive resource for a researcher planning to conduct their first metabolomics analysis. It is also useful for experienced researchers to update themselves on the latest trends in metabolomics.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Metabolomics
/
Honey
Language:
En
Journal:
J Sep Sci
Year:
2024
Document type:
Article
Affiliation country:
India