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Fluconazole and propolis co-encapsulated in chitosan nanoparticles for the treatment of vulvovaginal candidiasis in a murine model.
da Silva, Jacqueline Teixeira; Dantas de Sousa, Paulo Henrique; Costa, Adelaide Fernandes; de Menezes, Liliana Borges; Alves, Suzana Ferreira; Pellegrini, Flavio; Amaral, Andre Correa.
Affiliation
  • da Silva JT; Laboratory of Nano & Biotechnology, Institute of Tropical Pathology and Public Health, Universidade Federal de Goiás, St 235 university sector, Goiânia, GO, 74605-050, Brazil.
  • Dantas de Sousa PH; Laboratory of Nano & Biotechnology, Institute of Tropical Pathology and Public Health, Universidade Federal de Goiás, St 235 university sector, Goiânia, GO, 74605-050, Brazil.
  • Costa AF; Laboratory of Nano & Biotechnology, Institute of Tropical Pathology and Public Health, Universidade Federal de Goiás, St 235 university sector, Goiânia, GO, 74605-050, Brazil.
  • de Menezes LB; Laboratory of Pathology, Universidade Federal de Goiás, St 235 university sector, Goiânia, GO, 74605-050, Brazil.
  • Alves SF; Pharmacy Course, School of Medical Sciences, Pharmaceuticals and Biomedical Sciences, Pontifícia Universidade Católica de Goiás, Av university, 1440, Goiânia, GO, 74175-120, Brazil.
  • Pellegrini F; Company Citrinitas, St Pedroso Alvarenga, 505, São Paulo, SP, 04531-930, Brazil.
  • Amaral AC; Laboratory of Nano & Biotechnology, Institute of Tropical Pathology and Public Health, Universidade Federal de Goiás, St 235 university sector, Goiânia, GO, 74605-050, Brazil.
Med Mycol ; 61(11)2023 Nov 06.
Article in En | MEDLINE | ID: mdl-37947253
Vulvovaginal candidiasis is a fungal infection for which we search for alternatives for its treatment. Thus, a nanoparticle formulation based on fluconazole and green propolis was developed. These nanoparticles were tested, and we obtained adequate results in laboratory tests.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Candidiasis, Vulvovaginal / Chitosan / Nanoparticles Limits: Animals Language: En Journal: Med Mycol Journal subject: MEDICINA VETERINARIA / MICROBIOLOGIA Year: 2023 Document type: Article Affiliation country: Brazil
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Propolis / Candidiasis, Vulvovaginal / Chitosan / Nanoparticles Limits: Animals Language: En Journal: Med Mycol Journal subject: MEDICINA VETERINARIA / MICROBIOLOGIA Year: 2023 Document type: Article Affiliation country: Brazil