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Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failure.
Qian, Ke; Tang, Jie; Ling, Yue-Juan; Zhou, Ming; Yan, Xin-Xin; Xie, Yu; Zhu, Lu-Jia; Nirmala, Koju; Sun, Kang-Yun; Qin, Zheng-Hong; Sheng, Rui.
Affiliation
  • Qian K; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Tang J; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Ling YJ; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Zhou M; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Yan XX; Department of Cardiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215008, China.
  • Xie Y; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Zhu LJ; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Nirmala K; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Sun KY; Department of Cardiology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, 215008, China.
  • Qin ZH; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China.
  • Sheng R; Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences of Soochow University, Suzhou, 215123, China. Electronic address: shengrui@suda.edu.cn.
EBioMedicine ; 98: 104863, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37950995
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotonic Agents / Cardiomegaly / Energy Metabolism / Sirtuin 3 / Heart Failure / NADP Limits: Adult / Animals / Humans Language: En Journal: EBioMedicine Year: 2023 Document type: Article Affiliation country: China Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cardiotonic Agents / Cardiomegaly / Energy Metabolism / Sirtuin 3 / Heart Failure / NADP Limits: Adult / Animals / Humans Language: En Journal: EBioMedicine Year: 2023 Document type: Article Affiliation country: China Country of publication: Netherlands