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Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
Brotman, Sarah M; El-Sayed Moustafa, Julia S; Guan, Li; Broadaway, K Alaine; Wang, Dongmeng; Jackson, Anne U; Welch, Ryan; Currin, Kevin W; Tomlinson, Max; Vadlamudi, Swarooparani; Stringham, Heather M; Roberts, Amy L; Lakka, Timo A; Oravilahti, Anniina; Silva, Lilian Fernandes; Narisu, Narisu; Erdos, Michael R; Yan, Tingfen; Bonnycastle, Lori L; Raulerson, Chelsea K; Raza, Yasrab; Yan, Xinyu; Parker, Stephen C J; Kuusisto, Johanna; Pajukanta, Päivi; Tuomilehto, Jaakko; Collins, Francis S; Boehnke, Michael; Love, Michael I; Koistinen, Heikki A; Laakso, Markku; Mohlke, Karen L; Small, Kerrin S; Scott, Laura J.
Affiliation
  • Brotman SM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • El-Sayed Moustafa JS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Guan L; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • Wang D; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Welch R; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Currin KW; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • Tomlinson M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Vadlamudi S; Department of Medical and Molecular Genetics, King's College London, London, UK.
  • Stringham HM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • Roberts AL; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
  • Lakka TA; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Oravilahti A; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.
  • Silva LF; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
  • Narisu N; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.
  • Erdos MR; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.
  • Yan T; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.
  • Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Raulerson CK; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Raza Y; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Yan X; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Parker SCJ; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.
  • Kuusisto J; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Pajukanta P; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.
  • Tuomilehto J; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
  • Collins FS; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.
  • Boehnke M; Department of Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland.
  • Love MI; Department of Human Genetics and Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.
  • Laakso M; Department of Public Health, University of Helsinki, Helsinki, Finland.
  • Mohlke KL; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.
  • Small KS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  • Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
bioRxiv ; 2023 Oct 27.
Article in En | MEDLINE | ID: mdl-37961277

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Systematic_reviews Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Systematic_reviews Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States