Acquired factor VII deficiency in pediatric inflammatory bowel disease: Report of three cases.
Arab J Gastroenterol
; 24(4): 256-258, 2023 Nov.
Article
in En
| MEDLINE
| ID: mdl-37993374
ABSTRACT
Bleeding disorders can exacerbate gastrointestinal bleeding in inflammatory bowel disease (IBD) at the time of diagnosis or flares. Factor VII (FVII) deficiency is a life-threatening rare congenital bleeding disorder in childhood. This study describes three adolescent patients with IBD accompanied by acquired FVII deficiency. This is the first case series of patients with IBD accompanied by FVII deficiency. We hypothesized that inflammation, accelerated consumption, disease severity, and weight loss can cause decreased FVII activity in patients diagnosed with IBD. To control intestinal bleeding, we must keep in mind factor deficiencies in IBD.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Inflammatory Bowel Diseases
/
Factor VII Deficiency
Limits:
Adolescent
/
Child
/
Humans
Language:
En
Journal:
Arab J Gastroenterol
Year:
2023
Document type:
Article