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The neutral CB1 antagonist AM6527 reduces ethanol seeking, binge-like consumption, reinforcing, and withdrawal effects in male and female mice.
Raghav, Jimit Girish; Kumar, Hritik; Ji, Lipin; Vemuri, Kiran; Makriyannis, Alexandros; Suh, Junghyup; Leonard, Michael Z; Dang, Vivi; Ty, Chelsea; Marandola, Stephen; Kane, Natalie; Witt, Annika S; Shaqour, Samar; Miczek, Klaus A.
Affiliation
  • Raghav JG; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA.
  • Kumar H; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA.
  • Ji L; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA.
  • Vemuri K; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA.
  • Makriyannis A; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA. a.makriyannis@northeastern.edu.
  • Suh J; Division of Depression and Anxiety Disorders, Department of Psychiatry, Harvard Medical School, Mclean Hospital, Belmont, MA, 02478, USA.
  • Leonard MZ; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Dang V; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Ty C; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Marandola S; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Kane N; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Witt AS; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Shaqour S; Dept. of Psychology, Tufts University, 530 Boston Ave (Bacon Hall), Medford, MA, 02155, USA.
  • Miczek KA; Center for Drug Discovery, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA. Klaus.Miczek@tufts.edu.
Psychopharmacology (Berl) ; 241(3): 427-443, 2024 Mar.
Article in En | MEDLINE | ID: mdl-38001264

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Substance Withdrawal Syndrome / Alcoholism Limits: Animals / Female / Humans / Male Language: En Journal: Psychopharmacology (Berl) Year: 2024 Document type: Article Affiliation country: United States Country of publication: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Substance Withdrawal Syndrome / Alcoholism Limits: Animals / Female / Humans / Male Language: En Journal: Psychopharmacology (Berl) Year: 2024 Document type: Article Affiliation country: United States Country of publication: Germany