An Adapted GeneSwitch Toolkit for Comparable Cellular and Animal Models: A Proof of Concept in Modeling Charcot-Marie-Tooth Neuropathy.

Morant, Laura; Petrovic-Erfurth, Maria-Luise; Jordanova, Albena

Morant, Laura; Petrovic-Erfurth, Maria-Luise; Jordanova, Albena.

Affiliation

Morant L; Center for Molecular Neurology, VIB, University of Antwerp, 2610 Antwerpen, Belgium.
Petrovic-Erfurth ML; Department of Biomedical Sciences, University of Antwerp, 2610 Antwerpen, Belgium.
Jordanova A; Center for Molecular Neurology, VIB, University of Antwerp, 2610 Antwerpen, Belgium.

Int J Mol Sci ; 24(22)2023 Nov 09.

Article in En | MEDLINE | ID: mdl-38003325

Subject(s)

Charcot-Marie-Tooth Disease; Tyrosine-tRNA Ligase; Animals; DNA, Complementary/metabolism; Charcot-Marie-Tooth Disease/genetics; Charcot-Marie-Tooth Disease/metabolism; Drosophila/genetics; Mutation; Neurons/metabolism; Tyrosine-tRNA Ligase/metabolism; Disease Models, Animal; Mammals/genetics

Key words

CharcotMarieTooth neuropathy; Drosophila melanogaster; GeneSwitch™; aminoacyl tRNA-synthetase; disease modelling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tyrosine-tRNA Ligase / Charcot-Marie-Tooth Disease Limits: Animals Language: En Journal: Int J Mol Sci Year: 2023 Document type: Article Affiliation country: Belgium Country of publication: Switzerland

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