[Mechanisms of thrombocyte aggregation in experimental hypoparathyroidism]. / Issledovanie mekhanizmov agregatsii trombotsitov pri éksperimental'nom gipoparatireoze.

ABSTRACT

Inhibitors of thromboxane synthetase (imidazole), cyclooxygenase (indomethacin), phospholipase A2 (Mepacrine) were used in the experiments on rabbits with experimental hypoparathyroidism to study the role of aggregation factors in the changes of ADP- and collagen-induced platelet aggregation. The enhancement of arachidonic acid metabolism and the release of platelet aggregation factor are discussed.