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Host-derived oxidized phospholipids initiate effector-triggered immunity fostering lethality upon microbial encounter.
Gioia, Marco Di; Poli, Valentina; Tan, Piao J; Spreafico, Roberto; Chu, Anne; Cuenca, Alex G; Gordts, Philip Lsm; Pandolfi, Laura; Meloni, Federica; Witztum, Joseph L; Chou, Janet; Springstead, James R; Zanoni, Ivan.
Affiliation
  • Gioia MD; Harvard Medical School and Boston Children's Hospital, Division of Immunology and Division of Gastroenterology, MA 02115, USA.
  • Poli V; Harvard Medical School and Boston Children's Hospital, Division of Immunology and Division of Gastroenterology, MA 02115, USA.
  • Tan PJ; Department of Chemical and Paper Engineering, Western Michigan University, Kalamazoo, MI, USA.
  • Spreafico R; Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, CA, USA.
  • Chu A; Harvard Medical School and Boston Children's Hospital, Division of Immunology and Division of Gastroenterology, MA 02115, USA.
  • Cuenca AG; Department of Surgery, Boston Children's Hospital, Boston, MA 02115, USA; Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, MA 02114, USA.
  • Gordts PL; Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA; Glycobiology Research and Training Center, University of California, San Diego, La Jolla, California, USA.
  • Pandolfi L; Respiratory Disease Unit IRCCS San Matteo Hospital Foundation, and Department of Internal Medicine and Pharmacology, University of Pavia, Pavia, 27100, Italy Pavia, 27100, Italy.
  • Meloni F; Respiratory Disease Unit IRCCS San Matteo Hospital Foundation, and Department of Internal Medicine and Pharmacology, University of Pavia, Pavia, 27100, Italy Pavia, 27100, Italy.
  • Witztum JL; Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Chou J; Harvard Medical School and Boston Children's Hospital, Division of Immunology and Division of Gastroenterology, MA 02115, USA.
  • Springstead JR; Department of Chemical and Paper Engineering, Western Michigan University, Kalamazoo, MI, USA.
  • Zanoni I; Harvard Medical School and Boston Children's Hospital, Division of Immunology and Division of Gastroenterology, MA 02115, USA.
bioRxiv ; 2023 Nov 21.
Article in En | MEDLINE | ID: mdl-38045410
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2023 Document type: Article Affiliation country: United States