Formulation development and evaluation of nasal <i>in situ</i> gel of promethazine hydrochloride.

Boraste, Surabhi V; Patil, Sanjay B

Formulation development and evaluation of nasal in situ gel of promethazine hydrochloride.

Boraste, Surabhi V; Patil, Sanjay B.

Affiliation

Boraste SV; SNJB'S Shriman Suresh Dada Jain College of Pharmacy, Chandwad, Maharashtra, India.
Patil SB; SNJB'S Shriman Suresh Dada Jain College of Pharmacy, Chandwad, Maharashtra, India.

Drug Dev Ind Pharm ; 50(1): 11-22, 2024 Jan.

Article in En | MEDLINE | ID: mdl-38054848

Subject(s)

Antiemetics; Promethazine; Humans; Promethazine/metabolism; Promethazine/pharmacology; Administration, Intranasal; Nasal Mucosa/metabolism; Antiemetics/metabolism; Excipients/metabolism; Gels/pharmacology; Drug Delivery Systems/methods

Key words

Promethazine hydrochloride; ex-vivo diffusion; gelation temperature; intranasal in situ gel; mucoadhesive agent; poloxamer 407

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Promethazine / Antiemetics Limits: Humans Language: En Journal: Drug Dev Ind Pharm Year: 2024 Document type: Article Affiliation country: India Country of publication: United kingdom

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