Introduction of Carbonyl Groups into Antibodies.

Gulyak, Evgeny L; Alferova, Vera A; Korshun, Vladimir A; Sapozhnikova, Ksenia A

Gulyak, Evgeny L; Alferova, Vera A; Korshun, Vladimir A; Sapozhnikova, Ksenia A.

Affiliation

Gulyak EL; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.
Alferova VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.
Korshun VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.
Sapozhnikova KA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.

Molecules ; 28(23)2023 Dec 01.

Article in En | MEDLINE | ID: mdl-38067618

Subject(s)

Antineoplastic Agents; Immunoconjugates; Antibodies; Immunoconjugates/therapeutic use; Antigens; Drug Delivery Systems; Antineoplastic Agents/therapeutic use

Key words

ADC; UAAs; antibodies; biorthogonal reactions; carbonyl groups; glycans; glycans oxidation; immunoglobulins modification; oxime ligation; periodate oxidation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Immunoconjugates / Antineoplastic Agents Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2023 Document type: Article Affiliation country: RUSSIA

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google