Evidence of direct interaction between cisplatin and the caspase-cleaved prostate apoptosis response-4 tumor suppressor.

Raut, Krishna K; Pandey, Samjhana; Kharel, Gyanendra; Pascal, Steven M

Raut, Krishna K; Pandey, Samjhana; Kharel, Gyanendra; Pascal, Steven M.

Affiliation

Raut KK; Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, Virginia, USA.
Pandey S; Biomedical Sciences Program, Old Dominion University, Norfolk, Virginia, USA.
Kharel G; Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, Virginia, USA.
Pascal SM; Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, Virginia, USA.

Protein Sci ; 33(3): e4867, 2024 Mar.

Article in En | MEDLINE | ID: mdl-38093605

Subject(s)

Antineoplastic Agents; Cisplatin; Male; Humans; Cisplatin/pharmacology; Cisplatin/chemistry; Caspases; Prostate; Apoptosis; Cell Line, Tumor; Antineoplastic Agents/pharmacology

Key words

UV-vis absorption spectroscopy; atomic absorption spectroscopy (AAS); caspase-cleaved prostate apoptosis response-4 (cl-Par-4); circular dichroism (CD) spectroscopy; cisplatin; direct interaction; dynamic light scattering (DLS); inductively coupled plasma-optical emission spectroscopy (ICP-OES)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cisplatin / Antineoplastic Agents Limits: Humans / Male Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2024 Document type: Article Affiliation country: United States

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