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The mechanism of macroautophagy: The movie.
Reggiori, Fulvio; Boya, Patricia; da Costa, David; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Farrés, Judith; Guettler, Sebastian; Kraft, Claudine; Jungbluth, Heinz; Martinez, Ana; Morel, Etienne; Pless, Ole; Proikas-Cezanne, Tassula; Simonsen, Anne.
Affiliation
  • Reggiori F; Department of Biomedical Sciences of Cells & Systems, University of Groningen, University Medical Centre Groningen, 9713, AV Groningen, The Netherlands.
  • Boya P; Department of Biomedicine, Aarhus University, Ole Worms Allé 4, 8000 Aarhus C, Denmark.
  • da Costa D; Aarhus Institute of Advanced Studies (AIAS), Aarhus University, Høegh-Guldbergs Gade 6B, 8000 Aarhus C, Denmark.
  • Elazar Z; Centro de Investigaciones Biológicas Margarita Salas (CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain.
  • Eskelinen EL; Adjuvatis, 60 avenue Rockfeller, 69008 Lyon, France.
  • Farrés J; Department of Bimolecular Sciences, The Weizmann Institute of Science, 76100, Rehovot, Israel.
  • Guettler S; Institute of Biomedicine, University of Turku, 20520 Turku, Finland.
  • Kraft C; Anaxomics Biotech S.L., c. Diputació, 237 1-1 08007 Barcelona, Spain.
  • Jungbluth H; Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, London SM2 5NG, United Kingdom.
  • Martinez A; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
  • Morel E; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany.
  • Pless O; Randall Division of Cell and Molecular Biophysics, Muscle Signalling Section, King's College London, London, United Kingdom.
  • Proikas-Cezanne T; Department of Paediatric Neurology, Evelina Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom.
  • Simonsen A; Centro de Investigaciones Biomedicas en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Autophagy Rep ; 1(1): 414-417, 2022 Sep 14.
Article in En | MEDLINE | ID: mdl-38106995
ABSTRACT
This animated movie presents the mechanism of macroautophagy, hereafter autophagy, by showing the molecular features of the formation of autophagosomes, the hallmark organelle of this intracellular catabolic pathway. It is based on our current knowledge and it also illustrates how autophagosomes can recognize and eliminate selected cargoes.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Autophagy Rep Year: 2022 Document type: Article Affiliation country: Netherlands Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Autophagy Rep Year: 2022 Document type: Article Affiliation country: Netherlands Country of publication: United States