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Continued selection on cryptic SARS-CoV-2 observed in Missouri wastewater.
Gregory, Devon A; Rushford, Clayton; Hunter, Torin; Lin, Chung-Ho; Darby, Christie; Niehues, Nicole; Semkiw, Elizabeth; Reynolds, Melissa; Wenzel, Jeff; Johnson, Marc C.
Affiliation
  • Gregory DA; Department of Molecular Microbiology and Immunology, University of Missouri-School of Medicine, Columbia, Missouri, United States of America.
  • Rushford C; Department of Molecular Microbiology and Immunology, University of Missouri-School of Medicine, Columbia, Missouri, United States of America.
  • Hunter T; Department of Molecular Microbiology and Immunology, University of Missouri-School of Medicine, Columbia, Missouri, United States of America.
  • Lin CH; Center of Agroforestry, School of Natural Resources, University of Missouri, Columbia, Missouri, United States of America.
  • Darby C; Bureau of Environmental Epidemiology, Division of Community and Public Health, Missouri Department of Health and Senior Services, Jefferson City, Missouri, United States of America.
  • Niehues N; Bureau of Environmental Epidemiology, Division of Community and Public Health, Missouri Department of Health and Senior Services, Jefferson City, Missouri, United States of America.
  • Semkiw E; Bureau of Environmental Epidemiology, Division of Community and Public Health, Missouri Department of Health and Senior Services, Jefferson City, Missouri, United States of America.
  • Reynolds M; Bureau of Environmental Epidemiology, Division of Community and Public Health, Missouri Department of Health and Senior Services, Jefferson City, Missouri, United States of America.
  • Wenzel J; Bureau of Environmental Epidemiology, Division of Community and Public Health, Missouri Department of Health and Senior Services, Jefferson City, Missouri, United States of America.
  • Johnson MC; Department of Molecular Microbiology and Immunology, University of Missouri-School of Medicine, Columbia, Missouri, United States of America.
PLoS Pathog ; 19(12): e1011688, 2023 Dec.
Article in En | MEDLINE | ID: mdl-38153929
ABSTRACT
Deep sequencing of wastewater to detect SARS-CoV-2 has been used during the COVID-19 pandemic to monitor viral variants as they appear and circulate in communities. SARS-CoV-2 lineages of an unknown source that have not been detected in clinical samples, referred to as cryptic lineages, are sometimes repeatedly detected from specific locations. We have continued to detect one such lineage previously seen in a Missouri site. This cryptic lineage has continued to evolve, indicating continued selective pressure similar to that observed in Omicron lineages.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Country/Region as subject: America do norte Language: En Journal: PLoS Pathog Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Limits: Humans Country/Region as subject: America do norte Language: En Journal: PLoS Pathog Year: 2023 Document type: Article Affiliation country: United States Country of publication: United States