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In vitro activity of clindamycin, doxycycline, and trimethoprim/sulfamethoxazole against clinical isolates of ß-hemolytic Streptococcus spp. via BD Phoenix and broth microdilution.
Cho, Christian; Shields, Ryan K; Kline, Ellen G; Walsh, Thomas L; Jones, Chelsea E; Kasarda, Karen; Stefano, Kelly; Moffa, Matthew A; Bremmer, Derek N.
Affiliation
  • Cho C; Department of Pharmacy, Allegheny Health Network, Pittsburgh, PA, USA.
  • Shields RK; Antibiotic Management Program, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Kline EG; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Walsh TL; XDR Pathogens Laboratory, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
  • Jones CE; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Kasarda K; Division of Infectious Diseases, Allegheny Health Network, Pittsburgh, PA, USA.
  • Stefano K; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Moffa MA; Department of Pathology and Laboratory Medicine, Allegheny Health Network, Pittsburgh, PA, USA.
  • Bremmer DN; Department of Pathology and Laboratory Medicine, Allegheny Health Network, Pittsburgh, PA, USA.
Antimicrob Steward Healthc Epidemiol ; 3(1): e238, 2023.
Article in En | MEDLINE | ID: mdl-38156228
ABSTRACT
We tested 85 isolates of ß-hemolytic Streptococcus spp. against trimethoprim/sulfamethoxazole (TMP/SMX), clindamycin, and doxycycline by broth microdilution (BMD) and BD Phoenix. Susceptibility rates via BMD for TMP/SMX, clindamycin, and doxycycline were 100%, 85.5%, and 56.6%, respectively. TMP/SMX is a potential monotherapy agent for ß-hemolytic Streptococcus skin and soft tissue infections.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Steward Healthc Epidemiol Year: 2023 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Antimicrob Steward Healthc Epidemiol Year: 2023 Document type: Article Affiliation country: United States