First atroposelective Chan-Lam coupling for the synthesis of C-N linked biaryls.
Chem Commun (Camb)
; 60(6): 678-681, 2024 Jan 16.
Article
in En
| MEDLINE
| ID: mdl-38165949
ABSTRACT
The first atroposelective Chan-Lam coupling for the synthesis of C-N axial enantiomers is reported with good yields and ee. MnO2 additive is crucial for the success of the coupling. The longstanding problem of the lack of enantioselective synthesis to make chiral C-N linked atropisomers is solved.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2024
Document type:
Article
Affiliation country:
Japan