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Application of cell-free plasma next-generation sequencing technology in the diagnosis and management of pediatric meningitis.
Duster, Nicole; Ramchandar, Nanda; Foley, Jennifer; Farnaes, Lauge; Coufal, Nicole G.
Affiliation
  • Duster N; University of California San Diego, Department of Pediatrics, San Diego, CA, USA; Rady Children's Hospital, San Diego, CA, USA.
  • Ramchandar N; University of California San Diego, Department of Pediatrics, San Diego, CA, USA; Rady Children's Hospital, San Diego, CA, USA; Naval Medical Center San Diego, San Diego, CA, USA.
  • Foley J; Rady Children's Hospital, San Diego, CA, USA.
  • Farnaes L; University of California San Diego, Department of Pediatrics, San Diego, CA, USA; Rady Children's Hospital, San Diego, CA, USA.
  • Coufal NG; University of California San Diego, Department of Pediatrics, San Diego, CA, USA; Rady Children's Hospital, San Diego, CA, USA. Electronic address: ncoufal@health.ucsd.edu.
J Microbiol Methods ; 217-218: 106887, 2024.
Article in En | MEDLINE | ID: mdl-38169204
ABSTRACT
This retrospective study evaluates the clinical utility of CFPNGS in the diagnosis and management of pediatric meningitis. CFPNGS identified a causative pathogen in 36% of 28 subjects, compared to 50% for diverse conventional testing (57% combined). CFPNGS may be considered as an adjunct to standard testing.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Meningitis Type of study: Diagnostic_studies / Observational_studies Limits: Child / Humans Language: En Journal: J Microbiol Methods Year: 2024 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Meningitis Type of study: Diagnostic_studies / Observational_studies Limits: Child / Humans Language: En Journal: J Microbiol Methods Year: 2024 Document type: Article Affiliation country: United States