Diets intervene osteoporosis via gut-bone axis.
Gut Microbes
; 16(1): 2295432, 2024.
Article
in En
| MEDLINE
| ID: mdl-38174650
ABSTRACT
Osteoporosis is a systemic skeletal disease that seriously endangers the health of middle-aged and older adults. Recently, with the continuous deepening of research, an increasing number of studies have revealed gut microbiota as a potential target for osteoporosis, and the research concept of the gut-bone axis has gradually emerged. Additionally, the intake of dietary nutrients and the adoption of dietary patterns may affect the gut microbiota, and alterations in the gut microbiota might also influence the metabolic status of the host, thus adjusting bone metabolism. Based on the gut-bone axis, dietary intake can also participate in the modulation of bone metabolism by altering abundance, diversity, and composition of gut microbiota. Herein, combined with emerging literatures and relevant studies, this review is aimed to summarize the impacts of different dietary components and patterns on osteoporosis by acting on gut microbiota, as well as underlying mechanisms and proper dietary recommendations.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoporosis
/
Gastrointestinal Microbiome
Limits:
Aged
/
Humans
/
Middle aged
Language:
En
Journal:
Gut Microbes
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
United States