Perceived stress and progression of cardiometabolic risk factors among South Asians with prediabetes in a lifestyle intervention trial.
Prim Care Diabetes
; 18(2): 183-187, 2024 04.
Article
in En
| MEDLINE
| ID: mdl-38177017
ABSTRACT
AIMS:
To examine associations between perceived stress and cardiometabolic risk factors in South Asians with prediabetes and assess whether a diabetes prevention program mitigates the impact of stress on cardiometabolic health.METHODS:
We conducted a secondary analysis of the Diabetes Community Lifestyle Improvement Program, a lifestyle modification trial for diabetes prevention in India (n = 564). Indicators for cardiometabolic health (weight, waist circumference, blood pressure, glucose, HbA1c, and lipids) were measured at each visit while perceived stress was assessed via questionnaire at baseline. Multivariable linear regression assessed associations between stress and cardiometabolic parameters at baseline and 3-year follow up.RESULTS:
At baseline, perceived stress was associated with higher weight (b=0.16; 95% CI 0.04, 0.29) and waist circumference (b=0.11; 95% CI 0.01, 0.21) but lower 30-minute postload glucose (b=-0.44; 95% CI -0.76, -0.14) and LDL cholesterol (b=-0.40; 95% CI -0.76, -0.03). Over the study period, perceived stress was associated with weight gain (b=0.20; 95% CI 0.07, 0.33) and increased waist circumference (b=0.14; 95% CI 0.04, 0.24). Additionally, higher perceived stress was associated with lower HDL cholesterol among the control arm (pinteraction = 0.02).CONCLUSIONS:
Baseline stress was associated with negative cardiometabolic risk factor outcomes over time in those with prediabetes.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prediabetic State
/
Cardiovascular Diseases
/
Diabetes Mellitus
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Prim Care Diabetes
Journal subject:
ENDOCRINOLOGIA
Year:
2024
Document type:
Article
Country of publication:
United kingdom