Neutrophil extracellular traps in central nervous system (CNS) diseases.
PeerJ
; 12: e16465, 2024.
Article
in En
| MEDLINE
| ID: mdl-38188146
ABSTRACT
Excessive induction of inflammatory and immune responses is widely considered as one of vital factors contributing to the pathogenesis and progression of central nervous system (CNS) diseases. Neutrophils are well-studied members of inflammatory and immune cell family, contributing to the innate and adaptive immunity. Neutrophil-released neutrophil extracellular traps (NETs) play an important role in the regulation of various kinds of diseases, including CNS diseases. In this review, current knowledge on the biological features of NETs will be introduced. In addition, the role of NETs in several popular and well-studied CNS diseases including cerebral stroke, Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis (ALS), and neurological cancers will be described and discussed through the reviewing of previous related studies.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Central Nervous System Diseases
/
Extracellular Traps
/
Multiple Sclerosis
Limits:
Humans
Language:
En
Journal:
PeerJ
Year:
2024
Document type:
Article
Affiliation country:
China