Regulating Pathways of Bacillus pumilus Adamalysin-like Metalloendopeptidase Expression.
Int J Mol Sci
; 25(1)2023 Dec 20.
Article
in En
| MEDLINE
| ID: mdl-38203233
ABSTRACT
The minor secreted proteinase of B. pumilus 3-19 MprBp classified as the unique bacillary adamalysin-like enzyme of the metzincin clan. The functional role of this metalloproteinase in the bacilli cells is not clear. Analysis of the regulatory region of the mprBp gene showed the presence of potential binding sites to the transcription regulatory factors Spo0A (sporulation) and DegU (biodegradation). The study of mprBp activity in mutant strains of B. subtilis defective in regulatory proteins of the Spo- and Deg-systems showed that the mprBp gene is partially controlled by the Deg-system of signal transduction and independent from the Spo-system.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacillus
/
Bacillus pumilus
/
Lacticaseibacillus casei
Language:
En
Journal:
Int J Mol Sci
Year:
2023
Document type:
Article
Affiliation country:
RUSSIA
Country of publication:
Switzerland