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Regulating Pathways of Bacillus pumilus Adamalysin-like Metalloendopeptidase Expression.
Rudakova, Natalia L; Sabirova, Albina R; Khasanov, Damir I; Danilova, Iuliia V; Sharipova, Margarita R.
Affiliation
  • Rudakova NL; Institute of Fundamental Medicine, Kazan Federal University, Kremlevskaya St. 18, 420008 Kazan, Russia.
  • Sabirova AR; Institute of Fundamental Medicine, Kazan Federal University, Kremlevskaya St. 18, 420008 Kazan, Russia.
  • Khasanov DI; Institute of Fundamental Medicine, Kazan Federal University, Kremlevskaya St. 18, 420008 Kazan, Russia.
  • Danilova IV; Institute of Fundamental Medicine, Kazan Federal University, Kremlevskaya St. 18, 420008 Kazan, Russia.
  • Sharipova MR; Institute of Fundamental Medicine, Kazan Federal University, Kremlevskaya St. 18, 420008 Kazan, Russia.
Int J Mol Sci ; 25(1)2023 Dec 20.
Article in En | MEDLINE | ID: mdl-38203233
ABSTRACT
The minor secreted proteinase of B. pumilus 3-19 MprBp classified as the unique bacillary adamalysin-like enzyme of the metzincin clan. The functional role of this metalloproteinase in the bacilli cells is not clear. Analysis of the regulatory region of the mprBp gene showed the presence of potential binding sites to the transcription regulatory factors Spo0A (sporulation) and DegU (biodegradation). The study of mprBp activity in mutant strains of B. subtilis defective in regulatory proteins of the Spo- and Deg-systems showed that the mprBp gene is partially controlled by the Deg-system of signal transduction and independent from the Spo-system.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacillus / Bacillus pumilus / Lacticaseibacillus casei Language: En Journal: Int J Mol Sci Year: 2023 Document type: Article Affiliation country: RUSSIA Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacillus / Bacillus pumilus / Lacticaseibacillus casei Language: En Journal: Int J Mol Sci Year: 2023 Document type: Article Affiliation country: RUSSIA Country of publication: Switzerland