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Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol.
Kemmoku, Haruka; Takahashi, Kanoko; Mukai, Kojiro; Mori, Toshiki; Hirosawa, Koichiro M; Kiku, Fumika; Uchida, Yasunori; Kuchitsu, Yoshihiko; Nishioka, Yu; Sawa, Masaaki; Kishimoto, Takuma; Tanaka, Kazuma; Yokota, Yasunari; Arai, Hiroyuki; Suzuki, Kenichi G N; Taguchi, Tomohiko.
Affiliation
  • Kemmoku H; Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
  • Takahashi K; Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
  • Mukai K; Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
  • Mori T; United Graduate School of Agricultural Science, Gifu University, Gifu, Japan.
  • Hirosawa KM; Institute for Glyco-core Research (iGCORE), Gifu University, Gifu, Japan.
  • Kiku F; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Uchida Y; Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
  • Kuchitsu Y; Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan.
  • Nishioka Y; Research and Development, Carna Biosciences, Inc., Kobe, Japan.
  • Sawa M; Research and Development, Carna Biosciences, Inc., Kobe, Japan.
  • Kishimoto T; Division of Molecular Interaction, Institute for Genetic Medicine, Hokkaido University Graduate School of Life Science, Sapporo, Hokkaido, Japan.
  • Tanaka K; Division of Molecular Interaction, Institute for Genetic Medicine, Hokkaido University Graduate School of Life Science, Sapporo, Hokkaido, Japan.
  • Yokota Y; Department of EECE, Faculty of Engineering, Gifu University, Gifu, Japan.
  • Arai H; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo, Japan.
  • Suzuki KGN; Institute for Glyco-core Research (iGCORE), Gifu University, Gifu, Japan. suzuki.kenichi.b7@f.gifu-u.ac.jp.
  • Taguchi T; Division of Advanced Bioimaging, National Cancer Center Research Institute, Tokyo, Japan. suzuki.kenichi.b7@f.gifu-u.ac.jp.
Nat Commun ; 15(1): 220, 2024 Jan 11.
Article in En | MEDLINE | ID: mdl-38212328
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trans-Golgi Network / Lipoylation Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trans-Golgi Network / Lipoylation Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2024 Document type: Article Affiliation country: Japan Country of publication: United kingdom